This variety may not only help to avoid supply chain bottlenecks but could also promote broader acceptance of this method by improving the ease of self-collection.Ĭollection devices are inexpensive, easy to use, and yield testable samples. Our findings demonstrate the suitability of multiple device options for use in saliva collection kits. We found that all four devices enabled the consistent and safe collection of true saliva that was acceptable for SARS-CoV-2 diagnostic testing with a RT-qPCR-based assay ( Vogels et al. In this study, we evaluated the experience of thirty individuals who self-collected saliva using four different saliva collection devices: a P1000 pipette tip, a Salimetrics Saliva Collection Aid, a funnel, and a bulb pipette ( Fig. Equally important is establishing the acceptability of self-collection among the general public because methods that are deemed uncomfortable, difficult, or confusing are unlikely to gain traction in the population. Therefore, it is essential that self-collection of saliva is safe and can produce testable samples. Improper self-collection may also pose a safety risk if potentially biohazardous materials are mishandled. 2020).ĭespite these advantages, if saliva is collected improperly, it is difficult to handle in the laboratory ( Landry, Criscuolo, and Peaper 2020). Moreover, SARS-CoV-2 RNA is stable in saliva at a broad range of temperatures and for an extended period of time, obviating the need for preservatives or buffers that would increase the costs of collection tubes ( Ott et al. Self-collection of saliva is non-invasive and, unlike collection of nasopharyngeal swabs, does not require specialized training to perform ( Marty, Chen, and Verrill 2020). There is also a growing body of evidence that saliva can be used to detect other respiratory viruses and even co-infections ( Yoon et al. Saliva is an equally sensitive substrate for the detection of SARS-CoV-2 as nasopharyngeal swabs ( Wyllie et al. Self-collection of saliva for diagnostic testing is one such method. The COVID-19 pandemic has exacerbated the need for scalable methods designed to detect respiratory infections in the general population.
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